Bauhaus-Universität Weimar

Reports of Visits to Foreign Laboratories, vol. 7 (1932-33) [Illustrated Typoscript in 7 volumes] Reproduced with the kind permission of Dr. Cecil E. Leith
Benedict, Francis Gano
University of Edinburgh. Department of Physiology. 
Sir Edward Sharpey-Schafer. 
Schafer's age (83 years) and illness have both contributed to 
his lessened activities. (See figures There was no metabolism 
of humans going on, but he had a chamber for rabbits and cats. 
Schafer is strong on the use of cats and makes many experiments with 
them. He says they are fine experimental animals. Of special interest 
was the fact that they had begun work on a monkey. 
He was much interested in showing me the respiration apparatus 
for a cat, which I thought grotesquely bad. He was even more 
interested in showing me the apparatus for a rat which, if anything, 
was worse than the cat apparatus. (See figures b°[ and JO.) He used 
a Kendrick spirometer, so-called "Benedict" type, but everything was 
very badly constructed and extremely large for a rat. The blower 
sucked air out of the chamber (a large glass bell jar), through soda- 
lime by closed circuit, and then for some unaccountable reason there 
was placed a Sadd valve between the ventilation and spirometer. One 
point of interest was that the soda-lime was protected by an indicator 
which showed when carbon dioxide passed. This was the so-called 
"Sofnolite" which turned red when carbon dioxide was present. This 
is manufactured by Sofnol, Ltd., Greenwich, London. This Sofnolite 
that he used in a number of places to indicate the efficient carbon- 
dioxide absorption is all right, but I think that we are always as 
well protected with our various systems, as by the unusually large 
soda-lime bottle or else by using a pair of bottles, or with the closed 
circuit, having the air continually passing over the soda-lime, and 
that this control of unabsorbed carbon dioxide is practically unnecessary. 
These two apparatus in Schafer's laboratory are excellent illustrations 
of how badly respiratory metabolism may be attempted in a laboratory 
supposed to be one of the most important in Europe. It was sad to 
see such a "set-up" as this. 
Lecture. On October 5th I lectured in Schafer's lecture room 
for the Edinburgh Physiological Society, before an audience of 135. 
I gave the "third" lecture, which was followed by a lively discussion.


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