Bauhaus-Universität Weimar

Reports of Visits to Foreign Laboratories, vol. 2 (1910) [Illustrated Typoscript in 7 volumes] Reproduced with the kind permission of Dr. Cecil E. Leith
Benedict, Francis Gano
Dr. Ryffel. 
Dr. Eyffel has made a number of experiments on the formation of 
lactic acid in the body. He finds that in 100 cubic centimeters of 
normal urine there are 6 milligrams of lactic acid. Glycuronic acid 
interferes with the reaction, but if this is removed by lead subacetate, 
it also lowers the actual lactic acid, and a correction must be made. If 
he performs muscular work by running about the laboratory, he can increase 
the lactic acid up to 0.05 grams of lactic acid in 100 cubic centimeters 
of urine. Ho finds that there is very little relationship between the 
lactic acid and the sugar in the urine of diabetics, and believes that 
it plays but a very small rôle. As yet he has found no disease with 
a great amount of lactic acid. Dr. Ryffel impressed me as being a very 
serious and studiou.s individual, I think that his work can be absolutely 
relied upon.


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