Bauhaus-Universität Weimar

Handbook for the Physiological Laboratory. Text
Burdon-Sanderson, John Scott E. Klein Michael Foster T. Lauder Brunton
Section I.—Unstriped Muscle. 
The elements of this tissue are cells—the so-called “ contractile 
fibre-cells’’—of varying length, and for the most part spindle- 
shaped, this form being often modified by a flattening of the cells 
where they come in contact. Their ends are either single 01 
divided. Their substance is, in the fresh state, a pale or finelj 
granular protoplasm, sometimes longitudinally striated : in the 
thicker part of the cell lies an oblong, compressed nucleus, rather 
rounded at the extremities (thus becoming staff-shaped), or 
pointed. The nucleus contains one or two large shining nucle¬ 
oli : if single, the nucleolus lies in the centre of the nucleus ; if 
double, one is found at each extremity. External to the nucleus, 
and in a straight line with its longitudinal axis, some small 
granules may sometimes be seen. The unstriped muscular 
fibres are always arranged in bundles, the elements of which are; 
separated from each other bv interstitial substance. The bundles 
are held together by connective tissue, in which they lie in such 
a way that they either form membranes (as in the intestine) or 
mesh works (as in the bladder). In the former case, the bundles 
are parallel and mostly undivided ; in the latter, they run in 
various directions, divide frequently, and intercommunicate with 
each other. 
The best materials for the study of involuntary muscular fibre, 
are the bladder of the frog, the mesentery of the newt, the mus¬ 
cular coats of the intestines of the frog and mammalia, and 
arteries, such as those at the root of the mesentery of the frog. 
They may be demonstrated either in connection or isolated. 
To show their arrangement, a portion of the bladder of the 
frog may be spread on the glass slide with the mucous surface 
downwards, and covered in half per cent, salt solution. In such a 
preparation it is seen that a meshwork is formed by the repeated 
division of the bundles of fibres. If the bit is soaked for a few


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